Cardiac arrest accounts for 7-9 million deaths annually, 81% of cases are non-shockable, and only 4% survive a non-shockable cardiac arrest today.

Today's CPR only replaces 35% of blood flow, which is not enough to resuscitate most patients; and does not buy enough time to bridge patients to advanced treatments.

An estimated 81% of all cardiac arrest patients present as non-shockable, making them ineligible for defibrillation. Today, only 4% of these patients survive (PMID: 33248155). Non-shockable cardiac arrest cannot be treated with defibrillators. To survive a cardiac arrest, a patient must maintain blood flow to both the brain and the heart and achieve a return of spontaneous circulation (a regained heartbeat) or conversion to a shockable rhythm, either of which makes the patient eligible to be bridged to additional therapy.

The NEURESCUE device consists of a catheter and a handheld console. By temporarily inflating a balloon in the aorta, it redirects blood flow to the heart and brain, supercharging circulation to the most critical organs, thereby increasing resuscitation rates.

20%

Cardiac arrest is a major health problem accounting for an estimated 20% of all premature deaths.

81%

81% of all cardiac arrest patients present as non-shockable, making them ineligible for defibrillation, and only 4% survive a non-shockable cardiac arrest today.

35%

Today's CPR only replaces 35% of blood flow, which is not enough to resuscitate most patients; and does not buy enough time to bridge patients to advanced treatments.

Protecting the brain

The brain is subject to decreased blood flow during a cardiac arrest, preventing time for advanced treatments and leading to brain damage. Aortic occlusion during cardiac arrest increases the cerebral perfusion pressure with 200% as compared to standard treatment.

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September 2002

Effect of intra-aortic occlusion balloon in external thoracic compressions during CPR in pigs

Protecting the heart

Nine studies of aortic balloon occlusion in models of cardiac arrest have shown substantial increases in both coronary artery flow and coronary perfusion pressure. Coronary perfusion pressure (CPP) is principal in achieving survival, i.e. return of spontaneous circulation (ROSC). The higher the CPP, the higher the likelihood of achieving ROSC.

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March 2021

Randomized blinded trial of automated REBOA during CPR in a porcine model of cardiac arrest

May 2017

The role of resuscitative endovascular balloon occlusion of the aorta (REBOA) as an adjunct to ACLS in non-traumatic cardiac arrest